David Barnes‐Seeman

Author

David Barnes‐Seeman

Harvard University ORCID

Also Known As

D. BARNES‐SEEMAN, David Barnes-Seeman, David Barnes‐Seeman

Publications

797

Citations

H-Index

Concepts

All Affiliations

Harvard University Novartis (Switzerland)Howard Hughes Medical Institute Novartis Institutes for BioMedical Research

About

David Barnes‐Seeman is an author at Harvard University specializing in medicine, natural sciences, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	353
2	Natural Sciences	4	4	247
3	Biomolecular Engineering	3	3	200
4	Biochemistry	2	2	40
5	Cell Biology	1	1	133

David Barnes‐Seeman

Publications

721

Citations

H-Index

Page 1

	Year	Citations
A Robust Small-Molecule Microarray Platform for Screening Cell Lysates James E. Bradner, Olivia M. McPherson, Ralph Mazitschek, Chemistry & Biology Functional GenomicsScreening Cell LysatesComputational BiologyCell BiologyGene Expression Profiling	2006	133
Metabolically Stable <i>tert</i> -Butyl Replacement David Barnes‐Seeman, Monish Jain, Leslie Bell, ACS Medicinal Chemistry Letters	2013	127
Expanding the Functional Group Compatibility of Small‐Molecule Microarrays: Discovery of Novel Calmodulin Ligands David Barnes‐Seeman, Seung Bum Park, Angela N. Koehler, Angewandte Chemie International Edition Combinatorial ChemistryMolecular BiologyOrganic ChemistryNovel Calmodulin LigandsChemistry	2003	105
A Two-Step Total Synthesis of the Natural Pentacycle Trichodimerol, a Novel Inhibitor of TNF-α Production David Barnes‐Seeman, E. J. Corey Organic Letters Medicinal ChemistryEnantioselective SynthesisNatural SciencesMedicineDiversity-oriented Synthesis	1999	75
The formyl CH--O hydrogen bond as a key to transition-state organization in enantioselective allylation, aldol and Diels-Alder reactions catalyzed by chiral lewis acids E. J. Corey, David Barnes‐Seeman, Thomas Lee Tetrahedron Letters	1997	65
The formyl CH--O hydrogen bond as a critical factor in enantioselective reactions of aldehydes, part 4. Aldol, ethylation, hydrocyanation and Diels-Alder reactions catalyzed by chiral B, Ti and Al lewis acids E. J. Corey, David Barnes‐Seeman, Thomas Lee Tetrahedron Letters	1997	52
A transition-state model for the mikami enantioselective ene reaction E. J. Corey, David Barnes‐Seeman, Thomas Lee, Tetrahedron Letters Natural SciencesTransition-state ModelQuantum ChemistryChemistryReaction Process	1997	47
The mechanistic basis for diastereoselectivity in the Matteson rearrangement E. J. Corey, David Barnes‐Seeman, Thomas Lee Tetrahedron Asymmetry Pattern FormationThixotropyMatteson RearrangementPhysicsAnisotropic Material	1997	30
Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands Jeffrey T. Bagdanoff, Thomas M. Smith, Martin Allan, Cell chemical biology	2023	25
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach Edwige Lorthiois, James Roache, David Barnes‐Seeman, Journal of Medicinal Chemistry	2020	22

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