Publication | Closed Access
A Two-Step Total Synthesis of the Natural Pentacycle Trichodimerol, a Novel Inhibitor of TNF-α Production
75
Citations
12
References
1999
Year
Medicinal ChemistryEnantioselective SynthesisNatural SciencesMedicineDiversity-oriented SynthesisTwo-step Total SynthesisOrganic ChemistryTnf-α ProductionStereoselective SynthesisChemistryRemarkable DimerizationPharmacologyPharmaceutical ChemistrySynthetic ChemistryBiomolecular EngineeringDrug DiscoveryNatural Pentacycle TrichodimerolNatural Product Synthesis
[formula: see text] Trichodimerol (1) can be synthesized by a remarkable dimerization of the chiral hydroxy dienone 5.
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