Angela N. Koehler

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

Yingwei Mao, Xuecai Ge, Christopher L. Frank et al. · Cell · 2009 · 781 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Printing Small Molecules as Microarrays and Detecting Protein−Ligand Interactions en Masse

Gavin MacBeath, Angela N. Koehler, Stuart L. Schreiber · Journal of the American Chemical Society · 1999 · 423 citations

Life Sciences, Biochemistry, Chemical Biology +12

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

Paul A. Clemons, Nicole E. Bodycombe, Hyman A. Carrinski et al. · Proceedings of the National Academy of Sciences · 2010 · 352 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Identifying the proteins to which small-molecule probes and drugs bind in cells

Shao‐En Ong, Monica Schenone, Adam A. Margolin et al. · Proceedings of the National Academy of Sciences · 2009 · 307 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A small molecule that binds Hedgehog and blocks its signaling in human cells

Benjamin Z. Stanton, Lee F. Peng, Nicole Maloof et al. · Nature Chemical Biology · 2009 · 287 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11