Kim S. Beyer

Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C

Andreas Weiss, Edwige Lorthiois, Louise Barys et al. · Cancer Discovery · 2022 · 134 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Analysis of reelin as a candidate gene for autism

Elena Bonora, Kim S. Beyer, Janine A. Lamb et al. · Molecular Psychiatry · 2003 · 128 citations

Life Sciences, Genetics, Neuroscience +11

A Mutation Hot Spot for Nonspecific X-Linked Mental Retardation in the MECP2 Gene Causes the PPM-X Syndrome

Sabine M. Klauck, Susan Lindsay, Kim S. Beyer et al. · The American Journal of Human Genetics · 2002 · 123 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene

Elena Bacchelli, Francesco Blasi, Marianna Biondolillo et al. · Molecular Psychiatry · 2003 · 116 citations

Life Sciences, Genetics, Molecular Genetics +14

JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRAS^G12C for the Treatment of Solid Tumors

Edwige Lorthiois, Marc Gerspacher, Kim S. Beyer et al. · Journal of Medicinal Chemistry · 2022 · 95 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17