C. Truman

Structures of closed and open conformations of dimeric human ATM

Domagoj Baretić, Hannah Pollard, David I. Fisher et al. · Science Advances · 2017 · 128 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives

Julie A. Tucker, Neil Bennett, C. Brassington et al. · PLoS ONE · 2012 · 56 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Generating Selective Leads for Mer Kinase Inhibitors—Example of a Comprehensive Lead-Generation Strategy

J. Willem M. Nissink, Sana Bazzaz, Carolyn Blackett et al. · Journal of Medicinal Chemistry · 2021 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Completing the structural family portrait of the human EphB tyrosine kinase domains

R. Overman, J.E. Debreczeni, C. Truman et al. · Protein Science · 2014 · 25 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

A-loop interactions in Mer tyrosine kinase give rise to inhibitors with two-step mechanism and long residence time of binding

A. Pflug, Marianne Schimpl, J. Willem M. Nissink et al. · Biochemical Journal · 2020 · 24 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13