Hannah Pollard

Structural Basis of Substrate Methylation and Inhibition of SMYD2

Andrew D. Ferguson, Nicholas Larsen, Tina Howard et al. · Structure · 2011 · 193 citations · Full text

Biochemistry, Natural Sciences, Epigenetic Change +7

Structures of closed and open conformations of dimeric human ATM

Domagoj Baretić, Hannah Pollard, David I. Fisher et al. · Science Advances · 2017 · 124 citations · Full text

Geometry, Protein Assembly, Closed Conformation +18

Discovery of 5-Chloro-<i>N</i>²-[(1<i>S</i>)-1-(5-fluoropyrimidin-2-yl)ethyl]-<i>N</i>⁴-(5-methyl-1<i>H</i>-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a Novel Inhibitor of the Jak/Stat Pathway

Stephanos Ioannidis, Michelle L. Lamb, Tao Wang et al. · Journal of Medicinal Chemistry · 2010 · 123 citations · Full text

Novel Inhibitor, Potent Jak2 Inhibitor, Chemical Biology +24

Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases

Les A. Dakin, M. Block, Huawei Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 100 citations · Full text

Medicinal Chemistry, Novel Benzylidene-1,3-thiazolidine-2,4-diones, Biochemistry +11

Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane

P. Kevin Legan, Richard J. Goodyear, Matías Morin et al. · Human Molecular Genetics · 2013 · 56 citations · Full text

Genetics, Molecular Genetics, Different Tecta +24