William Westlin

Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC

Annette O. Walter, Robert Tjin Tham Sjin, Henry J. Haringsma et al. · Cancer Discovery · 2013 · 622 citations · Full text

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Robert Svensson, Seth J. Parker, Lillian J. Eichner et al. · Nature Medicine · 2016 · 501 citations · Full text

Tumor Biology, Oncology, Oncogenic Agent +12

Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma

James Lally, Sarani Ghoshal, Danielle K. DePeralta et al. · Cell Metabolism · 2018 · 395 citations · Full text

Oxysterol, Biochemistry, Medicine +8

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Geraldine Harriman, Jeremy R. Greenwood, Sathesh Bhat et al. · Proceedings of the National Academy of Sciences · 2016 · 275 citations · Full text

Fatty Liver Disease, Insulin Signaling, Metabolic Syndrome +18

Magnetic resonance contrast enhancement of neovasculature with ?v?3-targeted nanoparticles

Stasia A. Anderson, Randall K. Rader, William Westlin et al. · Magnetic Resonance in Medicine · 2000 · 273 citations · Full text

Nanoparticles, Nanomedicine, Targeted Contrast Agent +15