Rocco J. Galante

Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

Scott C. Mayer, Anthony F. Kreft, Boyd L. Harrison et al. · Journal of Medicinal Chemistry · 2008 · 111 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

A Thio-Diels−Alder Route to the Azocine Ring System. Total Synthesis of (±)-Otonecine

Edwin Vedējs, Rocco J. Galante, Peter G. Goekjian · Journal of the American Chemical Society · 1998 · 66 citations

Natural Sciences, Chemistry, Medicinal Chemistry +12

Discovery of N₁-(6-Chloroimidazo[2,1-<i>b</i>][1,3]thiazole-5-sulfonyl)tryptamine as a Potent, Selective, and Orally Active 5-HT₆Receptor Agonist

Derek C. Cole, Joseph R. Stock, William J. Lennox et al. · Journal of Medicinal Chemistry · 2007 · 58 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Development of a Pilot-Plant-Scale Synthesis of an Alkylated Dihydrobenzothiadiazole <i>S</i>,<i>S</i>-Dioxide: Incorporation of a Late-Stage Mitsunobu Reaction

Terrence J. Connolly, Waldemar P. Auguscinski, P. C. W. Fung et al. · Organic Process Research & Development · 2010 · 15 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Development of a Suitable Process for the Preparation of a TNF-α Converting Enzyme Inhibitor, WAY-281418

Youchu Wang, Maria Papamichelakis, Warren Chew et al. · Organic Process Research & Development · 2008 · 13 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10