William J. Lennox

Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1<i>H</i>-indole Derivatives as Potent, Selective 5-HT₆Receptor Agonists and Antagonists

Derek C. Cole, William J. Lennox, Sabrina Lombardi et al. · Journal of Medicinal Chemistry · 2004 · 102 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Moderate Antagonist Activity +13

Discovery of N₁-(6-Chloroimidazo[2,1-<i>b</i>][1,3]thiazole-5-sulfonyl)tryptamine as a Potent, Selective, and Orally Active 5-HT₆Receptor Agonist

Derek C. Cole, Joseph R. Stock, William J. Lennox et al. · Journal of Medicinal Chemistry · 2007 · 57 citations · Full text

Neuropsychology, Drug Target, Psychopharmacology +19

N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists

Derek C. Cole, John W. Ellingboe, William J. Lennox et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 43 citations · Full text

Functional Selectivity, Medicine, Pharmacological Agent +4

Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists

Derek C. Cole, William J. Lennox, Joseph R. Stock et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 34 citations · Full text

Molecular Pharmacology, Functional Selectivity, Medicine +6