Paul Fleming - Concepedia

Author

Paul Fleming

Millennium Engineering and Integration (United States)ORCID

Also Known As

P. E. FLEMING, P. E. Fleming, P. FLEMING, P. Fleming, Paul E. Fleming, Paul Fleming

Publications

2.5K

Citations

H-Index

Concepts

All Affiliations

Millennium Engineering and Integration (United States)Blueprint Medicines (United States)Takeda (United States)Takeda (Japan)University of Washington

About

Paul Fleming is an author at Millennium Engineering and Integration (United States) specializing in natural sciences, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	1.1K
2	Natural Sciences	6	6	554
3	Biochemistry	6	6	205
4	Engineering	3	3	172
5	Health Sciences	2	2	504

Paul Fleming

Publications

2.2K

Citations

H-Index

Page 1

	Year	Citations
Evaluation of the Proteasome Inhibitor MLN9708 in Preclinical Models of Human Cancer Erik Kupperman, Edmund C. Lee, Yueying Cao, Cancer Research Proteasome Inhibitor Mln9708Antitumor ActivityImmunologyProteasomeMolecular Biology	2010	488
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment Marc L. Hyer, Michael A. Milhollen, Jeff Ciavarri, Nature Medicine MedicineAnti-cancer AgentSmall-molecule InhibitorDrug DevelopmentBiomolecular Engineering	2018	414
Precision Targeted Therapy with BLU-667 for <i>RET</i>-Driven Cancers Vivek Subbiah, Justin F. Gainor, Rami Rahal, Cancer Discovery	2018	386
Parallel synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines by a new three-component condensation Christopher Blackburn, Bing Guan, Paul Fleming, Tetrahedron Letters Natural SciencesDiversity-oriented SynthesisOrganic ChemistryParallel SynthesisChemistry	1998	361
Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S β5-subunit Christopher Blackburn, Kenneth M. Gigstad, Paul Hales, Biochemical Journal	2010	144
Biosynthesis of taxoids. Mode of formation of the taxol side chain Paul Fleming, Ursula Mocek, Heinz G. Floss Journal of the American Chemical Society BiologyBiosynthesisEngineeringBiochemistryDonut Icon	1993	66
Genetic transformation of mature Taxus: an approach to genetically control the in vitro production of the anticancer drug, taxol Kyung-Hwan Han, Paul Fleming, Kevin D. Walker, Plant Science BiosynthesisEngineeringOncogenic AgentMature TaxusGenetics	1994	62
Biosynthesis of Taxoids. Mode of Attachment of the Taxol Side Chain Paul Fleming, Andrew R. Knaggs, Xian-Guo He, Journal of the American Chemical Society EngineeringAltmetric Attention ScoreSecondary MetaboliteBibliometricsOrganic Chemistry	1994	44
Preclinical evaluation of the antitumor activity of bortezomib in combination with vitamin C or with epigallocatechin gallate, a component of green tea Bret Bannerman, Ling Xu, Matthew D. Jones, Cancer Chemotherapy and Pharmacology	2011	40
Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome Christopher Blackburn, Cynthia Barrett, Jonathan L. Blank, Bioorganic & Medicinal Chemistry Letters Protein ChemistryMedicinal ChemistryP3 Threonine ResidueBiochemistryNatural Sciences	2010	40

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