Robin A. E. Carr

Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B

Rob L. M. van Montfort, Miles Congreve, Dominic Tisi et al. · Nature · 2003 · 637 citations

Redox Signaling, Biochemistry, Natural Sciences +8

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

Anne Cleasby, Jeff Yon, Philip J. Day et al. · PLoS ONE · 2014 · 250 citations · Full text

Molecular Biology, Btb Domain, Chemical Biology +17

Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency

Philip D. Edwards, Jeffrey S. Albert, Mark Sylvester et al. · Journal of Medicinal Chemistry · 2007 · 210 citations · Full text

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Adrian L. Gill, Martyn Frederickson, Anne Cleasby et al. · Journal of Medicinal Chemistry · 2004 · 185 citations · Full text

Combinatorial Chemistry, Drug Target, Hit Identification +18

Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase

Miles Congreve, David Aharony, Jeffrey S. Albert et al. · Journal of Medicinal Chemistry · 2007 · 141 citations · Full text