L. J. Goutas

Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.

F. M. Sirotnak, D. M. Moccio, L. E. Kelleher et al. · PubMed · 1981 · 189 citations

Kinetic Properties, Mixed-phenotype Acute Leukemia, Resistant Phenotypes +19

New folate analogs of the 10-deaza-aminopterin series Basis for structural design and biochemical and pharmacologic properties

Francis M. Sirotnak, Joseph I. DeGraw, D. M. Moccio et al. · Cancer Chemotherapy and Pharmacology · 1984 · 143 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +10

New folate analogs of the 10-deaza-aminopterin series

Francis M. Sirotnak, Joseph I. DeGraw, Franz A. Schmid et al. · Cancer Chemotherapy and Pharmacology · 1984 · 137 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +3

Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse.

Lawrence L. Samuels, L. J. Goutas, David G. Priest et al. · PubMed · 1986 · 53 citations

Normal Tissues, Cellular Enzymology, Biochemistry +13

Carrier-mediated transport of folate compounds in L1210 cells

Francis M. Sirotnak, L. J. Goutas, Donna M. Jacobsen et al. · Biochemical Pharmacology · 1987 · 44 citations

Biochemistry, Folate Compounds, Natural Sciences +6