Francis M. Sirotnak - Concepedia

Author

Francis M. Sirotnak

Also Known As

F M Sirotnak, F. M. SIROTNAK, F. M. Sirotnak, F.M Sirotnak, F.M. Sirotnak, FRANCIS M. SIROTNAK, Francis M Sirotnak, Francis M. Sirotnak, Francis Sirotnak, Sirotnak, F M

196

Publications

6.6K

Citations

H-Index

117

Concepts

All Affiliations

Memorial Sloan Kettering Cancer Center Cornell University Kettering University SRI International Southern Research Institute

About

Francis M. Sirotnak is an author at Memorial Sloan Kettering Cancer Center specializing in medicine, pharmacology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	33	75	3.7K
2	Natural Sciences	22	34	1.5K
3	Health Sciences	9	9	273
4	Public Health	2	2	152
5	Engineering	1	1	25

Francis M. Sirotnak

130

Publications

5.8K

Citations

H-Index

Page 1

	Year	Citations
Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Francis M. Sirotnak, Maureen F. Zakowski, V.A. Miller, PubMed ImmunologyPharmacotherapyHuman Tumor XenograftsTumor BiologyCancer Cell Biology	2000	761
Expression and Differential Polarization of the Reduced-folate Transporter-1 and the Folate Receptor α in Mammalian Retinal Pigment Epithelium Christy D. Chancy, Ramesh Kekuda, Wei Huang, Journal of Biological Chemistry	2000	151
New folate analogs of the 10-deaza-aminopterin series Basis for structural design and biochemical and pharmacologic properties Francis M. Sirotnak, Joseph I. DeGraw, D. M. Moccio, Cancer Chemotherapy and Pharmacology Bioorganic ChemistryBiochemistryNatural SciencesMedicinePeptide Library	1984	143
New folate analogs of the 10-deaza-aminopterin series Francis M. Sirotnak, Joseph I. DeGraw, Franz A. Schmid, Cancer Chemotherapy and Pharmacology Bioorganic ChemistryBiochemistryNatural SciencesPeptide SynthesisNew Folate Analogs	1984	137
Adaptive regulation of intestinal folate uptake: effect of dietary folate deficiency Hamid M. Said, Nabendu Sekhar Chatterjee, Riaz ul Haq, American Journal of Physiology-Cell Physiology Intestinal Folate UptakeNutritionDigestive TractDietary Folate DeficiencyAdaptive Regulation	2000	136
On the nature of a transport alteration determining resistance to amethopterin in the L1210 leukemia. Francis M. Sirotnak, Soji Kurita, Dorris J. Hutchison PubMed L1210 LeukemiaMixed-phenotype Acute LeukemiaMichaelis-menten KineticsChemical BiologyCellular Physiology	1968	127
Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts. Monica Motwani, Christoph P. Jung, Francis M. Sirotnak, PubMed Tumor BiologyTumor RegressionOncologyChemoprevention StrategyMedicine	2001	118
Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics Mona D. Lee, Yuhong She, Michael J. Soskis, Journal of Clinical Investigation Bioorganic ChemistryAntibiotic AdjuvantMolecular BiologyAntimicrobial ChemotherapyChemical Biology	2004	111
Syntheses and antifolate activity of 5-methyl-5-deaza analogs of aminopterin, methotrexate, folic acid, and N10-methylfolic acid James R. Piper, G. S. MCCALEB, Jane Montgomery, Journal of Medicinal Chemistry	1986	105
Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer. Francis M. Sirotnak, Yohung She, Fei Lee, PubMed	2002	103

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