Elizabeth T. Ener

MEN1 mutations mediate clinical resistance to menin inhibition

Florian Perner, Eytan M. Stein, Daniela V. Wenge et al. · Nature · 2023 · 214 citations · Full text

Genetics, Resistance Mutation (Virology), Men1 Mutations +4

A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death

Darko Bosnakovski, Meiricris Tomaz da Silva, Sithara T. Sunny et al. · Science Advances · 2019 · 67 citations · Full text

Histone Modifications, Chromatin, Facioscapulohumeral Muscular Dystrophy +15

Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression

Darko Bosnakovski, Micah D. Gearhart, Erik A. Toso et al. · Scientific Reports · 2018 · 66 citations · Full text

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability

Jonathan M. Tsai, Jacob D. Aguirre, Yen-Der Li et al. · Molecular Cell · 2023 · 66 citations · Full text

Molecular Regulation, Retinoic Acid, Molecular Biology +18

Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice

Darko Bosnakovski, Ahmed S. Shams, Ce Yuan et al. · Journal of Clinical Investigation · 2020 · 62 citations · Full text

Muscle Function, Transcriptional Regulation, Signaling Pathway +17