Daniela V. Wenge

MEN1 mutations mediate clinical resistance to menin inhibition

Florian Perner, Eytan M. Stein, Daniela V. Wenge et al. · Nature · 2023 · 214 citations · Full text

Genetics, Resistance Mutation (Virology), Men1 Mutations +4

Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in <i>KMT2A</i>- and <i>NPM1</i>-altered leukemias

Min Chul Kwon, Jan Willem Thuring, Olivier Querolle et al. · Blood · 2024 · 48 citations · Full text

Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of <i>KMT2A</i>-r and <i>NPM1c</i> AML

Wallace Bourgeois, Jevon Cutler, Brandon J. Aubrey et al. · Blood · 2023 · 24 citations · Full text

High-throughput diversification of protein-ligand surfaces to discover chemical inducers of proximity

James B. Shaum, Daniela V. Wenge, Hakyung Cheong et al. · 2024 · 17 citations · Full text

The future of HOXA-expressing leukemias: Menin inhibitor response and resistance

Daniela V. Wenge, Scott A. Armstrong · Current Opinion in Hematology · 2023 · 15 citations