Florian Perner

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

Andrei V. Krivtsov, Kathryn Evans, Jayant Y. Gadrey et al. · Cancer Cell · 2019 · 421 citations · Full text

Hematological Malignancy, Chromatin, Mll-rearranged Leukemia +9

The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia

Ghayas C. Issa, Ibrahim Aldoss, John F. DiPersio et al. · Nature · 2023 · 420 citations · Full text

MEN1 mutations mediate clinical resistance to menin inhibition

Florian Perner, Eytan M. Stein, Daniela V. Wenge et al. · Nature · 2023 · 214 citations · Full text

Genetics, Resistance Mutation (Virology), Men1 Mutations +4

Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms

Ashok Kumar Jayavelu, Tina M. Schnöder, Florian Perner et al. · Nature · 2020 · 150 citations

Transcriptional Regulation, Factor Ybx1, Cancer Genetics +5

The menin-MLL1 interaction is a molecular dependency in <i>NUP98</i>-rearranged AML

Emily Heikamp, Jill A. Henrich, Florian Perner et al. · Blood · 2021 · 131 citations · Full text

Nup98 Gene, Molecular Biology, Tumor Biology +19