Jacob D. Aguirre - Concepedia

Author

Jacob D. Aguirre

Western University ORCID

Also Known As

Aguirre, J. D., J.D. Aguirre, Jacob D Aguirre, Jacob D. Aguirre

Publications

790

Citations

H-Index

Concepts

All Affiliations

Western University Friedrich Miescher Institute University of Dundee University of Basel

About

Jacob D. Aguirre is an author at Western University specializing in medicine, cell biology, and cell signaling.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	225
2	Cell Biology	3	3	191
3	Engineering	1	1	52
4	Natural Sciences	1	1	66
5	Social Sciences	1	1	34

Jacob D. Aguirre

Publications

742

Citations

H-Index

Page 1

	Year	Citations
Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis Atul Kumar, Jacob D. Aguirre, Tara Condos, The EMBO Journal	2015	219
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease Donald E. Spratt, R.J. Martinez-Torres, Yeong Ju Noh, Nature Communications	2013	149
Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation Jacob D. Aguirre, Karen M. Dunkerley, Pascal Mercier, Proceedings of the National Academy of Sciences	2016	90
Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation Julius Rabl, R.D. Bunker, Andreas D. Schenk, Molecular Cell ChromatinGenome InstabilityCell RegulationMolecular RegulationImmunology	2019	73
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability Jonathan M. Tsai, Jacob D. Aguirre, Yen-Der Li, Molecular Cell Molecular RegulationRetinoic AcidMolecular BiologyNuclear Hormone ReceptorsTranscriptional Regulation	2023	66
Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation Tara Condos, Karen M. Dunkerley, E. Aisha Freeman, The EMBO Journal	2018	59
Orphan quality control shapes network dynamics and gene expression Kevin G. Mark, SriDurgaDevi Kolla, Jacob D. Aguirre, Cell Environmental SignalingEngineeringMolecular RegulationIntricate Protein NetworksGenetics	2023	52
Impact of altered phosphorylation on loss of function of juvenile Parkinsonism–associated genetic variants of the E3 ligase parkin Jacob D. Aguirre, Karen M. Dunkerley, Rica Lam, Journal of Biological Chemistry Neurodegenerative DiseasesNeurobiology Of DiseaseGenetic DisorderGeneticsAltered Phosphorylation	2018	34

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