PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

Sydney Gordon, Roy L. Maute, Ben W. Dulken, +10

Nature

InflammationCancer ImmunosurveillancePd-1 ExpressionImmunologyTumor Immunity +7

Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy

Amira Barkal, Kipp Weiskopf, Kevin S. Kao, +15

Nature Immunology

Cancer ImmunosurveillanceMhc ClassImmunologyImmunologic MechanismAntigen Processing +6

Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types

Kyle M. Loh, Angela Chen, Pang Wei Koh, +20

Cell

MechanobiologyInduced Pluripotent Stem CellDevelopmental BiologyBone Morphogenic ProteinMedicine +8

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging

Roy L. Maute, Sydney Gordon, Aaron T. Mayer, +10

Proceedings of the National Academy of Sciences

Small-molecule-induced polymerization triggers degradation of BCL6

Mikołaj Słabicki, Hojong Yoon, Jonas Koeppel, +18

Nature

EngineeringPolymer ScienceMolecular BiologyMacromolecular SystemPolymerization Kinetics +2

In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration

Yuval Rinkevich, Daniel T. Montoro, Humberto Contreras-Trujillo, +12

Cell Reports

Unifying mechanism for different fibrotic diseases

Gerlinde Wernig, Shih‐Yu Chen, Lu Cui, +8

Proceedings of the National Academy of Sciences

ImmunologyPathologyInflammationTranscriptional RegulationTissue Development +18

Coupled pre‐mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli

Amit Zeisel, Wolfgang J. Köstler, Natali Molotski, +8

Molecular Systems Biology

<i>Dnmt3a</i>-mutated clonal hematopoiesis promotes osteoporosis

Peter G. Kim, Abhishek Niroula, Veronica Shkolnik, +25

The Journal of Experimental Medicine

Complex mammalian-like haematopoietic system found in a colonial chordate

Benyamin Rosental, Mark Kowarsky, Jun Seita, +17

Nature

BiologyColonial ChordateMorphological EvidenceDevelopmental BiologyMammalogy +5