PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity

Sydney Gordon, Roy L. Maute, Ben W. Dulken, +10

Nature

InflammationCancer ImmunosurveillancePd-1 ExpressionImmunologyTumor Immunity +7

Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy

Amira Barkal, Kipp Weiskopf, Kevin S. Kao, +15

Nature Immunology

Cancer ImmunosurveillanceMhc ClassImmunologyImmunologic MechanismAntigen Processing +6

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging

Roy L. Maute, Sydney Gordon, Aaron T. Mayer, +10

Proceedings of the National Academy of Sciences

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy

Akanksha Chhabra, Aaron M. Ring, Kipp Weiskopf, +10

Science Translational Medicine

Cell TherapyHsc TransplantationImmunologyPathologyImmunotherapy +14

Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

Lu Cui, Shih‐Yu Chen, Tristan Lerbs, +7

Nature Communications

Computational Design of an α-Gliadin Peptidase

Sydney Gordon, Elizabeth J. Stanley, Sarah Wolf, +7

Journal of the American Chemical Society

GlycobiologyMolecular BiologyCeliac DiseaseProtein FoldingGluten Peptides +14

Practical Immuno-PET Radiotracer Design Considerations for Human Immune Checkpoint Imaging

Aaron T. Mayer, Arutselvan Natarajan, Sydney Gordon, +5

Journal of Nuclear Medicine

Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers

Jonathan M. Tsai, Rahul Sinha, Jun Seita, +17

Science Translational Medicine

Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

Lu Cui, Shih‐Yu Chen, Tristan Lerbs, +7