Donald E. Spratt

Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

Atul Kumar, Jacob D. Aguirre, Tara Condos et al. · The EMBO Journal · 2015 · 219 citations · Full text

A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease

Donald E. Spratt, R.J. Martinez-Torres, Yeong Ju Noh et al. · Nature Communications · 2013 · 149 citations · Full text

Selective Recruitment of an E2∼Ubiquitin Complex by an E3 Ubiquitin Ligase

Donald E. Spratt, Kenneth Wu, Jordan Kovacev et al. · Journal of Biological Chemistry · 2012 · 55 citations · Full text

Differential Binding of Calmodulin Domains to Constitutive and Inducible Nitric Oxide Synthase Enzymes

Donald E. Spratt, Valentina Taiakina, Michãel Palmer et al. · Biochemistry · 2007 · 53 citations

Cam Binding, Molecular Biology, Ca2+ Signal +20

Suramin inhibits cullin-RING E3 ubiquitin ligases

Kenneth Wu, Robert Chong, Qing Yu et al. · Proceedings of the National Academy of Sciences · 2016 · 53 citations · Full text