Joan S. Brugge

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Jayanta Debnath, Senthil K. Muthuswamy, Joan S. Brugge · Methods · 2003 · 2K citations

Developmental Biology, Mammary Gland, Morphogenesis +10

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Jason W. Locasale, Alexandra Grassian, Tamar Melman et al. · Nature Genetics · 2011 · 1.1K citations · Full text

Biochemistry, Phosphoglycerate Dehydrogenase, Catabolism +4

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

Zachary T. Schafer, Alexandra Grassian, Loling Song et al. · Nature · 2009 · 1K citations · Full text

Reductive Stress, Oxysterol, Biochemistry +12

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

Maria Rozakis-Adcock, Jane McGlade, Geraldine Mbamalu et al. · Nature · 1992 · 993 citations

Signal Transduction, Ras Pathway, Signaling Pathway +8

A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

Xiao-Jun Ma, Zuncai Wang, Paula D. Ryan et al. · Cancer Cell · 2004 · 947 citations · Full text

Breast Oncology, Breast Cancer Patients, Medicine +9