Senthil K. Muthuswamy

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

Jayanta Debnath, Senthil K. Muthuswamy, Joan S. Brugge · Methods · 2003 · 2K citations

Developmental Biology, Mammary Gland, Morphogenesis +10

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

Jayanta Debnath, Kenna R. Mills, Nicole L. Collins et al. · Cell · 2002 · 762 citations · Full text

Oncogene-expressing Mammary Acini, Developmental Biology, Cell Regulation +10

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

Ling Huang, Audrey Holtzinger, Ishaan Jagan et al. · Nature Medicine · 2015 · 737 citations · Full text

Induced Pluripotent Stem Cell, Patient-derived Tumor Organoids, Engineering +12

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

Senthil K. Muthuswamy, Dongmei Li, Sophie A. Lelièvre et al. · Nature Cell Biology · 2001 · 558 citations · Full text

Signal Transduction, Developmental Biology, Cell Division +10

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

Mauricio J. Reginato, Kenna R. Mills, Jessica K. Paulus et al. · Nature Cell Biology · 2003 · 556 citations

Pro-apoptotic Protein Bim, Signal Transduction, Signaling Pathway +10