Ling Huang

Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

Ling Huang, Audrey Holtzinger, Ishaan Jagan et al. · Nature Medicine · 2015 · 737 citations · Full text

Induced Pluripotent Stem Cell, Patient-derived Tumor Organoids, Engineering +12

Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Xiangpeng Dai, Wenjian Gan, Xiaoning Li et al. · Nature Medicine · 2017 · 333 citations · Full text

Molecular Biology, Bet Inhibitors, Spop Mutations +6

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression.

Elizabeth K. Bikoff, Ling Huang, Vasso Episkopou et al. · The Journal of Experimental Medicine · 1993 · 322 citations · Full text

Histocompatibility, Class Ii Alpha, Peptide Acquisition +17

Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly

Hui Wang, Sam Lacoche, Ling Huang et al. · Proceedings of the National Academy of Sciences · 2012 · 140 citations · Full text

Genome-wide synthetic lethal screen unveils novel CAIX-NFS1/xCT axis as a targetable vulnerability in hypoxic solid tumors

Shawn C. Chafe, Frederick S. Vizeacoumar, Geetha Venkateswaran et al. · Science Advances · 2021 · 127 citations · Full text