Concepedia
Statistics
Publications
46
Citations
3K
H-Index
26
Active since
1969
Affiliations
University of British Columbia(Current)
Commonwealth Scientific and Industrial Research Organisation
McMaster University
Western Forest Products
University of Florence
Shawn C. Chafe is an author at University of British Columbia specializing in medicine, botany, and forestry.
Top concepts
MedicineBotanyForestryCell BiologyBiologyNatural SciencesPlant PhysiologyEngineeringTumor BiologyCytoskeleton
Publications per year
1969–2024
Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis
Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi et al. · Nature · 2012 · 594 citations · Full text
Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Developmental Biology +8
Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche
Frances E. Lock, Paul C. McDonald, Y. Lou et al. · Oncogene · 2012 · 338 citations
Hypoxic Niche, Carbonic Anhydrase Ix, Biochemistry +7
Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia
Paul C. McDonald, Shawn C. Chafe, Wells S. Brown et al. · Gastroenterology · 2019 · 225 citations · Full text
Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically
Shawn C. Chafe, Paul C. McDonald, Saeed Saberi et al. · Cancer Immunology Research · 2019 · 153 citations
Carbonic Anhydrase IX Promotes Myeloid-Derived Suppressor Cell Mobilization and Establishment of a Metastatic Niche by Stimulating G-CSF Production
Shawn C. Chafe, Yuanmei Lou, Jaclyn Sceneay et al. · Cancer Research · 2015 · 129 citations · Full text
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