Jane McGlade

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Giuliana Pelicci, Luisa Lanfrancone, F Grignani et al. · Cell · 1992 · 1.3K citations

Signal Transduction, Signaling Pathway, Protein Expression +11

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

Maria Rozakis-Adcock, Jane McGlade, Geraldine Mbamalu et al. · Nature · 1992 · 993 citations

Signal Transduction, Ras Pathway, Signaling Pathway +8

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

Zhou Songyang, Steven E. Shoelson, Jane McGlade et al. · Molecular and Cellular Biology · 1994 · 878 citations · Full text

Structural Bioinformatics, Signal Recognition, Molecular Biology +22

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

Olivier Staub, Sascha E. Dho, P Henry et al. · The EMBO Journal · 1996 · 841 citations · Full text

Nedd4 Bind, Protein Function, Molecular Physiology +12

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

Leonardo Salmena, Bénédicte Lemmers, Anne Hakem et al. · Genes & Development · 2003 · 469 citations · Full text

Targeted Caspase 8, T-regulatory Cell, Apoptosis +17