Zuncai Wang

A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

Xiao-Jun Ma, Zuncai Wang, Paula D. Ryan et al. · Cancer Cell · 2004 · 947 citations · Full text

Breast Oncology, Breast Cancer Patients, Medicine +9

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel et al. · Nature Cell Biology · 2014 · 715 citations

Inflammation, Cell Autophagy, Signal Transduction +13

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Christina H. Eng, Zuncai Wang, Diane Tkach et al. · Proceedings of the National Academy of Sciences · 2015 · 221 citations · Full text

Kras Mutant Tumors, Autophagy Inhibitors, Immunology +17

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9

Jonathan M. Goodwin, William E. Dowdle, Rowena DeJesus et al. · Cell Reports · 2017 · 184 citations · Full text

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

Rowena DeJesus, Francesca Moretti, Gregory McAllister et al. · eLife · 2016 · 152 citations · Full text

Genetics, Crispr-mediated Genome, Molecular Biology +16