A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

Xiao-Jun Ma, Zuncai Wang, Paula D. Ryan, +27

Cancer Cell

Breast OncologyBreast Cancer PatientsMedicineTwo-gene Expression RatioPathology +7

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel, +44

Nature Cell Biology

InflammationCell AutophagySignal TransductionHeme HomeostasisIron Metabolism +11

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Christina H. Eng, Zuncai Wang, Diane Tkach, +17

Proceedings of the National Academy of Sciences

Kras Mutant TumorsAutophagy InhibitorsImmunologyPathologyCell Proliferation +15

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9

Jonathan M. Goodwin, William E. Dowdle, Rowena DeJesus, +9

Cell Reports

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

Rowena DeJesus, Francesca Moretti, Gregory McAllister, +21

eLife

GeneticsCrispr-mediated GenomeMolecular BiologyEpigeneticsFunctional Crispr +14

HOXB13 promotes ovarian cancer progression

Jiangyong Miao, Zuncai Wang, Heather L. Provencher, +6

Proceedings of the National Academy of Sciences

Breast OncologyActivated RasGynecologyOvarian Cancer ProgressionCancer Biology +14

The Prognostic Biomarkers <i>HOXB13, IL17BR</i>, and <i>CHDH</i> Are Regulated by Estrogen in Breast Cancer

Zuncai Wang, Sonika Dahiya, Heather L. Provencher, +6

Clinical Cancer Research

Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers

Jihua Hao, Adrian W.R. Serohijos, Gail Newton, +5

PLoS Computational Biology

Progesterone Receptor (hPR) Upregulates the Fibronectin Promoter Activity in Human Decidual Fibroblasts

Linda Tseng, Meiyi Tang, Zuncai Wang, +1

DNA and Cell Biology

Progesterone ReceptorReproductive HealthGynecologyMenstrual CycleHuman Decidual Fibroblasts +20

Identification of Elongation Factor G as the Conserved Cellular Target of Argyrin B

Beat Nyfeler, Dominic Hoepfner, Deborah Palestrant, +26

PLoS ONE

Molecular BiologyCytoskeletonCell GrowthCellular PhysiologyCyclic Octapeptides +17