William E. Dowdle

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel et al. · Nature Cell Biology · 2014 · 715 citations

Inflammation, Cell Autophagy, Signal Transduction +13

Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms

Kevin C. Corbit, Amy E. Shyer, William E. Dowdle et al. · Nature Cell Biology · 2007 · 503 citations

Developmental Biology, Signal Transduction, Cell Regulation +11

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

Sejeong Shin, Christopher A. Dimitri, Sang-Oh Yoon et al. · Molecular Cell · 2010 · 284 citations · Full text

Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD

Mark Y. Fang, Sebastian Markmiller, Anthony Q. Vu et al. · Neuron · 2019 · 263 citations · Full text

Reductive Stress, Tdp-43 Recruitment, Neurodegenerative Diseases +10

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9

Jonathan M. Goodwin, William E. Dowdle, Rowena DeJesus et al. · Cell Reports · 2017 · 184 citations · Full text