Sebastian Markmiller

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

Sebastian Markmiller, Sahar Soltanieh, Kari L. Server et al. · Cell · 2018 · 927 citations · Full text

Protein Function, Functional Genomics, Interactomics +11

Targeted degradation of sense and antisense <i>C9orf72</i> RNA foci as therapy for ALS and frontotemporal degeneration

Clotilde Lagier‐Tourenne, Michael W. Baughn, Frank Rigo et al. · Proceedings of the National Academy of Sciences · 2013 · 551 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Sporadic Als +13

Programmable RNA Tracking in Live Cells with CRISPR/Cas9

David A. Nelles, Mark Y. Fang, Mitchell R. O’Connell et al. · Cell · 2016 · 525 citations · Full text

Off-target Effect, Programmable Rna Tracking, Gene Editing +5

Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD

Mark Y. Fang, Sebastian Markmiller, Anthony Q. Vu et al. · Neuron · 2019 · 263 citations · Full text

Reductive Stress, Tdp-43 Recruitment, Neurodegenerative Diseases +10

Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9

Ranjan Batra, David A. Nelles, Elaine Pirie et al. · Cell · 2017 · 254 citations · Full text

Genetics, Genetic Engineering, Molecular Biology +7