Mark H. Bender

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 877 citations · Full text

Protein Secretion, Neurochemical Biomarkers, Amyloid Precursor Protein +17

Abstract 2819: Identification and characterization of a novel smoothened antagonist for the treatment of cancer with deregulated hedgehog signaling

Mark H. Bender, Philip A. Hipskind, Andrew Capen et al. · Cancer Research · 2011 · 49 citations

Abstract 2819, Pharmacotherapy, Cell Differentiation +22

P4-339 Stereoselective inhibition of amyloid beta peptide secretion by LY450139, a novel functional gamma secretase inhibitor

Bruce D. Gitter, Dan L. Czilli, Weiying Li et al. · Neurobiology of Aging · 2004 · 29 citations

Protein Secretion, Biochemistry, Medicine +7

P1-180 Reduction in a-beta(1-40) and A-beta(1-42) in CSF and plasma in the beagle dog following acute oral dosing of the gamma secretase inhibitor, LY450139

Paul A. Hyslop, Patrick C. May, James E. Audia et al. · Neurobiology of Aging · 2004 · 15 citations

Animal Physiology, Veterinary Physiology, P1-180 Reduction +7

P1-419 In vivo characterization of LY450139, a novel, stereoselective, functional gamma-secretase inhibitor

Leonard N. Boggs, Kimberly S. Fuson, Bruce D. Gitter et al. · Neurobiology of Aging · 2004 · 15 citations

Protein Secretion, Biochemistry, Functional Gamma-secretase Inhibitor +8