Leonard N. Boggs

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 879 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor

Patrick C. May, Robert A. Dean, Stephen L. Lowe et al. · Journal of Neuroscience · 2011 · 369 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans

Patrick C. May, Brian A. Willis, Stephen L. Lowe et al. · Journal of Neuroscience · 2015 · 205 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Neurotoxicity of Human Amylin in Rat Primary Hippocampal Cultures: Similarity to Alzheimer's Disease Amyloid‐<i>β</i> Neurotoxicity

Patrick C. May, Leonard N. Boggs, Kimberly S. Fuson · Journal of Neurochemistry · 1993 · 124 citations

Life Sciences, Neurobiology, Neuroscience +16

Clusterin (Apo J) Protects Against In Vitro Amyloid‐β(1–40) Neurotoxicity

Leonard N. Boggs, Kimberly S. Fuson, Melvyn Baez et al. · Journal of Neurochemistry · 1996 · 108 citations

Life Sciences, Neurobiology, Neuroscience +16