Paul A. Hyslop

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 877 citations · Full text

Protein Secretion, Neurochemical Biomarkers, Amyloid Precursor Protein +17

Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

Paul A. Hyslop, Daniel B. Hinshaw, W A Halsey et al. · Journal of Biological Chemistry · 1988 · 624 citations · Full text

Cell Death, Cell Death Mechanisms, Redox Biology +25

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

Ingrid U. Schraufstätter, Daniel B. Hinshaw, Paul A. Hyslop et al. · Journal of Clinical Investigation · 1986 · 513 citations · Full text

Dna Damage, Lipid Peroxidation, Molecular Biology +24

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.

Ingrid U. Schraufstätter, Paul A. Hyslop, Daniel B. Hinshaw et al. · Proceedings of the National Academy of Sciences · 1986 · 462 citations · Full text

Inflammation, Inflammatory Injury, Hydrogen Peroxide-induced Injury +14

Oxidant-induced DNA damage of target cells.

Ingrid U. Schraufstätter, Paul A. Hyslop, Janis H. Jackson et al. · Journal of Clinical Investigation · 1988 · 375 citations · Full text

Dna Damage, Dna Breakage, Lipid Peroxidation +17