Paul A. Hyslop

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

Harry F. Dovey, Varghese John, J. P. Anderson et al. · Journal of Neurochemistry · 2001 · 879 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

Paul A. Hyslop, Daniel B. Hinshaw, W A Halsey et al. · Journal of Biological Chemistry · 1988 · 624 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

Ingrid U. Schraufstätter, Daniel B. Hinshaw, Paul A. Hyslop et al. · Journal of Clinical Investigation · 1986 · 513 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase.

Ingrid U. Schraufstätter, Paul A. Hyslop, Daniel B. Hinshaw et al. · Proceedings of the National Academy of Sciences · 1986 · 462 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Oxidant-induced DNA damage of target cells.

Ingrid U. Schraufstätter, Paul A. Hyslop, Janis H. Jackson et al. · Journal of Clinical Investigation · 1988 · 377 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17