Concepedia

Author

Frédéric Donche

GlaxoSmithKline (France)

Also Known As

F. Donche, Frederic Donche, Frédéric Donche

7

Publications

540

Citations

6

H-Index

25

Concepts

All Affiliations

GlaxoSmithKline (France)GlaxoSmithKline (United Kingdom)
FD

About

Frédéric Donche is an author at GlaxoSmithKline (France) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

6

6

540

2

Biochemistry

4

4

215

3

Natural Sciences

3

3

98

4

Health Sciences

1

1

117

5

Biomolecular Engineering

1

1

207

Frédéric Donche

×

6

Publications

540

Citations

6

H-Index

YearCitations

Identification of a novel series of BET family bromodomain inhibitors: Binding mode and profile of I-BET151 (GSK1210151A)

Jonathan T. Seal, Yann Lamotte, Frédéric Donche,

Bioorganic & Medicinal Chemistry Letters

2012

207

From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151

Olivier Mirguet, Yann Lamotte, Frédéric Donche,

Bioorganic & Medicinal Chemistry Letters

2012

118

Substituted 2-[(4-Aminomethyl)phenoxy]-2-methylpropionic Acid PPARα Agonists. 1. Discovery of a Novel Series of Potent HDLc Raising Agents

Michael L. Sierra, Véronique Bénéton, Anne-Bénédict Boullay,

Journal of Medicinal Chemistry

2007

117

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase

Philip A. Harris, Nicolas Faucher, Nicolas George,

Journal of Medicinal Chemistry

2019

68

Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity

Marie-Hélène Fouchet, Frédéric Donche, Christelle Martin,

Bioorganic & Medicinal Chemistry

2008

16

Discovery of Pyridones As Oral AMPK Direct Activators

Olivier Mirguet, Stéphane Sautet, Catherine-Anne Clément,

ACS Medicinal Chemistry Letters

2013

14

Page 1