Publication | Open Access

Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity

Medicinal ChemistryOcular ToxicityPharmacological StudyBiochemistryNatural SciencesPharmacologyToxicologyPharmacotherapyDrug DevelopmentMedicine2,3-Oxidosqualene Cyclase InhibitorsLow Systemic ExposurePharmacokineticsDrug DiscoveryDrug Resistance