Anne-Bénédicte Boullay

Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains

Chun‐wa Chung, Hervé Coste, Julia H. White et al. · Journal of Medicinal Chemistry · 2011 · 335 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

From ApoA1 upregulation to BET family bromodomain inhibition: Discovery of I-BET151

Olivier Mirguet, Yann Lamotte, Frédéric Donche et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 118 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +6

Discovery and Optimization of Potent, Selective, and <i>in Vivo</i> Efficacious 2-Aryl Benzimidazole BCATm Inhibitors

Hongfeng Deng, Jingye Zhou, Flora S. Sundersingh et al. · ACS Medicinal Chemistry Letters · 2016 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits

Sophie M. Bertrand, Nicolas Ancellin, Benjamin Beaufils et al. · Journal of Medicinal Chemistry · 2015 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A Potent and Selective Kallikrein-5 Inhibitor Delivers High Pharmacological Activity in Skin from Patients with Netherton Syndrome

John Liddle, Véronique Bénéton, Matthew A. Benson et al. · Journal of Investigative Dermatology · 2021 · 32 citations

Medicine, Dermatology, Pharmacology +2