Hervé Coste

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

Dominique Toullec, P. Pianetti, Hervé Coste et al. · Journal of Biological Chemistry · 1991 · 2.5K citations · Full text

Pharmacy, Biochemistry, Pharmacology +11

Suppression of inflammation by a synthetic histone mimic

Edwige Nicodème, Kate L. Jeffrey, Uwe Schaefer et al. · Nature · 2010 · 1.6K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains

Chun‐wa Chung, Hervé Coste, Julia H. White et al. · Journal of Medicinal Chemistry · 2011 · 335 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

The Discovery of Tadalafil:  A Novel and Highly Selective PDE5 Inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1‘,2‘:1,6]pyrido[3,4-<i>b</i>]indole-1,4-dione Analogues

Alain Daugan, Pascal Grondin, Cécile Ruault et al. · Journal of Medicinal Chemistry · 2003 · 282 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Discovery of Tadalafil:  A Novel and Highly Selective PDE5 Inhibitor. 1: 5,6,11,11a-Tetrahydro-1<i>H</i>-imidazo[1‘,5‘:1,6]pyrido[3,4-<i>b</i>]indole-1,3(2<i>H</i>)-dione Analogues

Alain Daugan, Pascal Grondin, Cécile Ruault et al. · Journal of Medicinal Chemistry · 2003 · 194 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16