Edwige Nicodème

Suppression of inflammation by a synthetic histone mimic

Edwige Nicodème, Kate L. Jeffrey, Uwe Schaefer et al. · Nature · 2010 · 1.6K citations · Full text

Inflammation, Chromatin, Anti-inflammatory +8

Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

Susan Smith, Channa Jayawickreme, David J. Rickard et al. · Journal of Investigative Dermatology · 2017 · 351 citations · Full text

Inflammation, Natural Ahr Agonist, Anti-inflammatory +10

Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains

Chun‐wa Chung, Hervé Coste, Julia H. White et al. · Journal of Medicinal Chemistry · 2011 · 334 citations · Full text

Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains

Olivier Mirguet, Romain Gosmini, Jérôme Toum et al. · Journal of Medicinal Chemistry · 2013 · 301 citations · Full text

Histone Modifications, Chemoprevention Strategy, Epigenetic Change +22

The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor

Romain Gosmini, Van Loc Nguyen, Jérôme Toum et al. · Journal of Medicinal Chemistry · 2014 · 187 citations · Full text

Medicinal Chemistry, Histone Code, Drug Target +12