Pascal Grondin

Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

Matthew J. Sanders, Pascal Grondin, Bronwyn D. Hegarty et al. · Biochemical Journal · 2007 · 668 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Short-Term Overexpression of a Constitutively Active Form of AMP-Activated Protein Kinase in the Liver Leads to Mild Hypoglycemia and Fatty Liver

Marc Foretz, Nicolas Ancellin, Fabrizio Andréelli et al. · Diabetes · 2005 · 382 citations

Life Sciences, Biochemistry, Molecular Biology +17

Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

Jean‐Marie Brusq, Nicolas Ancellin, Pascal Grondin et al. · Journal of Lipid Research · 2006 · 341 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The Discovery of Tadalafil:  A Novel and Highly Selective PDE5 Inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1‘,2‘:1,6]pyrido[3,4-<i>b</i>]indole-1,4-dione Analogues

Alain Daugan, Pascal Grondin, Cécile Ruault et al. · Journal of Medicinal Chemistry · 2003 · 282 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Discovery of Tadalafil:  A Novel and Highly Selective PDE5 Inhibitor. 1: 5,6,11,11a-Tetrahydro-1<i>H</i>-imidazo[1‘,5‘:1,6]pyrido[3,4-<i>b</i>]indole-1,3(2<i>H</i>)-dione Analogues

Alain Daugan, Pascal Grondin, Cécile Ruault et al. · Journal of Medicinal Chemistry · 2003 · 194 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16