Jean‐Marie Brusq

Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

Jean‐Marie Brusq, Nicolas Ancellin, Pascal Grondin et al. · Journal of Lipid Research · 2006 · 341 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Discovery and Characterization of Small Molecule Inhibitors of the BET Family Bromodomains

Chun‐wa Chung, Hervé Coste, Julia H. White et al. · Journal of Medicinal Chemistry · 2011 · 335 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains

Olivier Mirguet, Romain Gosmini, Jérôme Toum et al. · Journal of Medicinal Chemistry · 2013 · 304 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor

Romain Gosmini, Van Loc Nguyen, Jérôme Toum et al. · Journal of Medicinal Chemistry · 2014 · 187 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Inhibition of TGF‐<i>β</i> signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine‐induced liver fibrosis

Anne‐Charlotte de Gouville, Valérie Boullay, Gaël Krysa et al. · British Journal of Pharmacology · 2005 · 165 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14