Nicolas George

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase

Philip A. Harris, Nicolas Faucher, Nicolas George et al. · Journal of Medicinal Chemistry · 2019 · 68 citations · Full text

Drug Target, Immunology, Efficacious Inhibitors +19

Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases

Mattias F. Lindberg, Emmanuel Deau, Jonas Arfwedson et al. · Journal of Medicinal Chemistry · 2023 · 39 citations · Full text

Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer’s Disease Drug Candidate

Mattias F. Lindberg, Emmanuel Deau, Frédéric Miege et al. · Journal of Medicinal Chemistry · 2023 · 30 citations · Full text

Crystal Structure, Drug Target, Bioorganic Chemistry +20

Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B

Emmanuel Deau, Mattias F. Lindberg, Frédéric Miege et al. · Journal of Medicinal Chemistry · 2023 · 28 citations · Full text

A Practical, One‐Pot Multicomponent Synthesis of α‐Amidosulfides and Their Application as Latent <i>N</i>‐Acylimines in the Friedel–Crafts Reaction

Nicolas George, Mathieu Bekkaye, Géraldine Masson et al. · European Journal of Organic Chemistry · 2011 · 26 citations · Full text

α‐Amidosulfides 4, Diversity Oriented Synthesis, One‐pot Multicomponent Synthesis +15