George V. Delucca

Cyclic HIV Protease Inhibitors:  Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas

Patrick Y. S. Lam, Yu Ru, Prabhakar K. Jadhav et al. · Journal of Medicinal Chemistry · 1996 · 170 citations · Full text

CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure–activity relationships

Dean A. Wacker, Joseph B. Santella, Daniel S. Gardner et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 46 citations · Full text

Asthma, Ccr3 Antagonists, Potential New Therapy +10

Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design

Ashvinikumar V. Gavai, Derek Norris, George V. Delucca et al. · Journal of Medicinal Chemistry · 2021 · 40 citations · Full text

From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: The discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis

Joseph B. Santella, Daniel S. Gardner, Wenqing Yao et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 30 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Acyclic Scaffolds +9

Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties

Matthew D. Hill, Haiquan Fang, Derek Norris et al. · ACS Medicinal Chemistry Letters · 2022 · 10 citations · Full text