Aesop Cho

Structural basis for RNA replication by the hepatitis C virus polymerase

T.C. Appleby, Jason K. Perry, Eisuke Murakami et al. · Science · 2015 · 344 citations

Viral Replication, Rna Replication, Viral Polymerase Structure +19

Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides

Aesop Cho, Oliver L. Saunders, Thomas Butler et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 214 citations · Full text

1′-Substituted 4-Aza-7,9-dideazaadenosine C-nucleosides, Biochemistry, Antiviral Activity +6

Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

Jamie J. Arnold, Suresh D. Sharma, Joy Y. Feng et al. · PLoS Pathogens · 2012 · 138 citations · Full text

Discovery of the First <i>C</i>-Nucleoside HCV Polymerase Inhibitor (GS-6620) with Demonstrated Antiviral Response in HCV Infected Patients

Aesop Cho, Lijun Zhang, Jie Xu et al. · Journal of Medicinal Chemistry · 2013 · 125 citations

Viral Polymerase Structure, Adenosine Analogs, Hepatitis C Virus +17

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model

Kiyoshi Nakayama, Haruko C. Kawato, Jun Watanabe et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 65 citations

Pyridopyrimidine Series, Antimicrobial Susceptibility, Medicine +9