Eisuke Murakami

Structural basis for RNA replication by the hepatitis C virus polymerase

T.C. Appleby, Jason K. Perry, Eisuke Murakami et al. · Science · 2015 · 352 citations

Life Sciences, Biology, Molecular Biology +17

Mechanism of Activation of PSI-7851 and Its Diastereoisomer PSI-7977

Eisuke Murakami, Tatiana Tolstykh, Haiying Bao et al. · Journal of Biological Chemistry · 2010 · 293 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The Mechanism of Action of β- <scp>d</scp> -2′-Deoxy-2′-Fluoro-2′- <i>C</i> -Methylcytidine Involves a Second Metabolic Pathway Leading to β- <scp>d</scp> -2′-Deoxy-2′-Fluoro-2′- <i>C</i> -Methyluridine 5′-Triphosphate, a Potent Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Eisuke Murakami, Congrong Niu, Haiying Bao et al. · Antimicrobial Agents and Chemotherapy · 2007 · 154 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

PSI-7851, a Pronucleotide of β- <scp>d</scp> -2′-Deoxy-2′-Fluoro-2′- <i>C</i> -Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication

Angela M. Lam, Eisuke Murakami, Christine Espiritu et al. · Antimicrobial Agents and Chemotherapy · 2010 · 140 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA

Ralph T. Mosley, Thomas E. Edwards, Eisuke Murakami et al. · Journal of Virology · 2012 · 119 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17