Haruko C. Kawato

Synthesis and Antifungal Activity of Rhodopeptin Analogues. 2. Modification of the West Amino Acid Moiety

Kiyoshi Nakayama, Haruko C. Kawato, Hiroaki Inagaki et al. · Organic Letters · 2000 · 86 citations

Pharmacy, Biochemistry, Medicinal Chemistry +13

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

Kiyoshi Nakayama, Yohei Ishida, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 82 citations

Pharmacy, Microbiology, Pharmacology +17

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model

Kiyoshi Nakayama, Haruko C. Kawato, Jun Watanabe et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 65 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 2: achieving activity in vivo through the use of alternative scaffolds

Kiyoshi Nakayama, Yohei Ishida, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Microbiology +15

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety

Kiyoshi Nakayama, Noriko Kuru, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 49 citations

Life Sciences, Medicinal Chemistry, Microbiology +14