Dmitri Wiederschain

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

William E. Dowdle, Beat Nyfeler, Jane Nagel et al. · Nature Cell Biology · 2014 · 715 citations

Inflammation, Cell Autophagy, Signal Transduction +13

PTEN-deficient cancers depend on PIK3CB

Susan Wee, Dmitri Wiederschain, Sauveur-Michel Maira et al. · Proceedings of the National Academy of Sciences · 2008 · 546 citations · Full text

Tumor Biology, Class Ia Pi3k, Signal Transduction +15

Single-vector inducible lentiviral RNAi system for oncology target validation

Dmitri Wiederschain, W Nicolson Susan, Lin Chen et al. · Cell Cycle · 2009 · 453 citations · Full text

Engineering, Oncology Target Validation, Cancer Biology +16

Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion

Kensuke Tateishi, Hiroaki Wakimoto, A. John Iafrate et al. · Cancer Cell · 2015 · 439 citations · Full text

Genome Instability, Cancer Genomics, Extreme Vulnerability +4

Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model

Jianmin Fang, Yuen Shing, Dmitri Wiederschain et al. · Proceedings of the National Academy of Sciences · 2000 · 390 citations · Full text