Tasos Gogakos

Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice

Jessica Vincent, Carolina Adura, Pu Gao et al. · Nature Communications · 2017 · 360 citations · Full text

Primary Macrophages, Innate Immune System, Immunology +21

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression

Lodoe Lama, Carolina Adura, Wei Xie et al. · Nature Communications · 2019 · 269 citations · Full text

Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers

Kemal M. Akat, D’Vesharronne Moore-McGriff, Pavel Morozov et al. · Proceedings of the National Academy of Sciences · 2014 · 246 citations · Full text

Human Heart Failure, Heart Failure, Engineering +21

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs

Aitor Garzia, Seyed Mehdi Jafarnejad, Cindy Meyer et al. · Nature Communications · 2017 · 224 citations · Full text

Human CLP1 Mutations Alter tRNA Biogenesis, Affecting Both Peripheral and Central Nervous System Function

Ender Karaca, Stefan Weitzer, Davut Pehli̇van et al. · Cell · 2014 · 220 citations · Full text

Affecting Both Peripheral, Knockout Mouse, Genome Instability +8