Denise L. Driscoll

2-Substituted Aminopyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-ones. Structure−Activity Relationships Against Selected Tyrosine Kinases and in Vitro and in Vivo Anticancer Activity

S. KLUTCHKO, James M. Hamby, Diane H. Boschelli et al. · Journal of Medicinal Chemistry · 1998 · 130 citations · Full text

Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib

Siquan Chen, Jonathan L. Blank, Theodore Peters et al. · Cancer Research · 2010 · 103 citations · Full text

Genome-wide Sirna Screen, Proteasome Inhibition Induces, Medicine +14

Anti-Angiogenic Activity of Selected Receptor Tyrosine Kinase Inhibitors, PD166285 and PD173074: Implications for Combination Treatment with Photodynamic Therapy

Charles J. Dimitroff, Wayne D. Klohs, Amarnath Sharma et al. · Investigational New Drugs · 1999 · 96 citations

Anti-angiogenic Activity, Angiogenesis, Photodynamic Therapy +11

Plk1 Inhibition Causes Post-Mitotic DNA Damage and Senescence in a Range of Human Tumor Cell Lines

Denise L. Driscoll, Arijit Chakravarty, Doug Bowman et al. · PLoS ONE · 2014 · 58 citations · Full text

Genome Instability, Cell Regulation, Cell Division +15

Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)

Matthew O. Duffey, Tricia J. Vos, Ruth Adams et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Tumor Biology +18