Thomas A. Kirkland

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

Andrew S. Dixon, Marie K. Schwinn, Mary P. Hall et al. · ACS Chemical Biology · 2015 · 1.4K citations

Immunocytochemical Technique, Engineering, Protein Assembly +23

NanoBRET—A Novel BRET Platform for the Analysis of Protein–Protein Interactions

Thomas Machleidt, Carolyn C. Woodroofe, Marie K. Schwinn et al. · ACS Chemical Biology · 2015 · 477 citations · Full text

Protein–protein Interactions, Engineering, Protein Assembly +18

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

James D. Vasta, Cesear Corona, Jennifer Wilkinson et al. · Cell chemical biology · 2017 · 281 citations · Full text

Drug Target, Wide-spectrum Kinase Profiling, Kinase Inhibitors +20

Target engagement and drug residence time can be observed in living cells with BRET

Matthew B. Robers, Melanie L. Dart, Carolyn C. Woodroofe et al. · Nature Communications · 2015 · 280 citations · Full text

Therapeutic Action, Drug Target, Cell Culture +22

Effects of Olefin Substitution on the Ring-Closing Metathesis of Dienes

Thomas A. Kirkland, Robert H. Grubbs · The Journal of Organic Chemistry · 1997 · 252 citations

Engineering, Heterocyclic, Alkene Metathesis +11