Melanie L. Dart

Target engagement and drug residence time can be observed in living cells with BRET

Matthew B. Robers, Melanie L. Dart, Carolyn C. Woodroofe et al. · Nature Communications · 2015 · 280 citations · Full text

Therapeutic Action, Drug Target, Cell Culture +22

Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rγnull mice

Deepika Rajesh, Ying Zhou, Ewa Jankowska−Gan et al. · Human Immunology · 2010 · 67 citations · Full text

Autoimmune Disease, Immune Cell Development, Immunodeficiencies +11

Interleukin-17–Dependent Autoimmunity to Collagen Type V in Atherosclerosis

Melanie L. Dart, Ewa Jankowska−Gan, Guorui Huang et al. · Circulation Research · 2010 · 57 citations · Full text

Homogeneous Assay for Target Engagement Utilizing Bioluminescent Thermal Shift

Melanie L. Dart, Thomas Machleidt, Emily Jost et al. · ACS Medicinal Chemistry Letters · 2018 · 53 citations · Full text

Target Engagement, Protein Function, Bioluminescence +15

Toward a Point-of-Need Bioluminescence-Based Immunoassay Utilizing a Complete Shelf-Stable Reagent

Mary P. Hall, Virginia A. Kincaid, Emily Jost et al. · Analytical Chemistry · 2021 · 33 citations

Immunocytochemical Technique, Engineering, Peptide Engineering +21