Matthew B. Robers

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

Mary P. Hall, James Unch, Brock F. Binkowski et al. · ACS Chemical Biology · 2012 · 1.6K citations · Full text

Engineering, Bioluminescence Methodologies, Molecular Biology +25

NanoBRET—A Novel BRET Platform for the Analysis of Protein–Protein Interactions

Thomas Machleidt, Carolyn C. Woodroofe, Marie K. Schwinn et al. · ACS Chemical Biology · 2015 · 477 citations · Full text

Protein–protein Interactions, Engineering, Protein Assembly +18

Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action

Kristin M. Riching, Sarah D. Mahan, Cesear Corona et al. · ACS Chemical Biology · 2018 · 305 citations · Full text

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

James D. Vasta, Cesear Corona, Jennifer Wilkinson et al. · Cell chemical biology · 2017 · 281 citations · Full text

Drug Target, Wide-spectrum Kinase Profiling, Kinase Inhibitors +20

Target engagement and drug residence time can be observed in living cells with BRET

Matthew B. Robers, Melanie L. Dart, Carolyn C. Woodroofe et al. · Nature Communications · 2015 · 280 citations · Full text

Therapeutic Action, Drug Target, Cell Culture +22