Thomas Machleidt

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

Mary P. Hall, James Unch, Brock F. Binkowski et al. · ACS Chemical Biology · 2012 · 1.6K citations · Full text

Engineering, Bioluminescence Methodologies, Molecular Biology +25

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

Andrew S. Dixon, Marie K. Schwinn, Mary P. Hall et al. · ACS Chemical Biology · 2015 · 1.4K citations

Immunocytochemical Technique, Engineering, Protein Assembly +23

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

Thomas Henkel, Thomas Machleidt, Irit Alkalay et al. · Nature · 1993 · 1.1K citations

Inflammation, Transcriptional Regulation, Signal Transduction +14

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

Stefan Schütze, Karin Potthoff, Thomas Machleidt et al. · Cell · 1992 · 1.1K citations

Inflammation, Signal Transduction, Apoptosis +8

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

Katja Wiegmann, Stefan Schütze, Thomas Machleidt et al. · Cell · 1994 · 724 citations

Inflammation, Tumor Necrosis Factor, Signal Transduction +10